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type strain genome server  (DSMZ)


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    Structured Review

    DSMZ type strain genome server
    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server <t>(TYGS),</t> places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
    Type Strain Genome Server, supplied by DSMZ, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/type+(strain)+genome+server/type++strain++genome+server/bio_rxiv__2025__07__17__665312-142-15-21
    Average 90 stars, based on 1 article reviews
    type strain genome server - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Exposure to third generation cephalosporin induces L-form transition in Shigella sonnei , potentially acting as a bacterial reservoir for persistent infection"

    Article Title: Exposure to third generation cephalosporin induces L-form transition in Shigella sonnei , potentially acting as a bacterial reservoir for persistent infection

    Journal: bioRxiv

    doi: 10.1101/2025.07.17.665312

    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server (TYGS), places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
    Figure Legend Snippet: (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server (TYGS), places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.

    Techniques Used: Functional Assay

    Related Articles

    Comparison:

    Article Title: The Whole Genome Sequencing Analysis of a Halophilic Streptomyces sp. C11-1
    Article Snippet: The complete genome sequence of a new halophilic Streptomyces sp. C11-1 was revealed and analyzed.. This strain was isolated from Dabancheng Salt Lake in Xinjiang, China.. It has strong antibacterial activity against drug-resistant Staphylococcus aureus and Staphylococcus epidermidis strains.

    Article Title: Genomic and Pangenomic Insights into Aeromonas salmonicida subsp. oncorhynchi subsp. nov.
    Article Snippet: .. The digital DNA–DNA hybridization (dDDH) analysis was performed using the Type Strain Genome Server (TYGS, https://tygs.dsmz.de/ , accessed on 20 February 2025), allowing comparison between strain A-9 T and reference type strains from the DSMZ database [ ]. ..

    Article Title: Genomic and Pangenomic Insights into Aeromonas salmonicida subsp. oncorhynchi subsp. nov.
    Article Snippet: .. The digital DNA–DNA hybridization (dDDH) analysis was performed using the Type Strain Genome Server (TYGS, https://tygs.dsmz.de/, accessed on 20 February 2025), allowing comparison between strain A-9T and reference type strains from the DSMZ database [16]. ..

    Next-Generation Sequencing:

    Article Title: Limitations of MALDI-TOF MS in identifying anaerobic bacteremia: challenges in polymicrobial infections and the role of whole-genome sequencing.
    Article Snippet: .. Genomic data obtained by NGS were registered in the Type Strain Genome Server (https://tygs.dsmz.de) and analyzed pairwise by dDDH with strain type. ..

    DNA-DNA Hybridization:

    Article Title: Genomic analysis of Pseudomonas sp. GWSMS-1 isolated from Antarctica reveals its potential in Chitin hydrolysis.
    Article Snippet: .. In addition, Average Nucleotide Identity (ANI) and digital DNA-DNA Hybridization (dDDH) analyses were performed using the OrthoANIu method ( h t t p s : / / w w w . e z b i o c l o u d . n e t / t o o l s / a n i) [11]and the Type Strain Genome Server (https://tygs.dsmz.de) [12], based on complete genome data. ..

    Article Title: Genomic and Pangenomic Insights into Aeromonas salmonicida subsp. oncorhynchi subsp. nov.
    Article Snippet: .. The digital DNA–DNA hybridization (dDDH) analysis was performed using the Type Strain Genome Server (TYGS, https://tygs.dsmz.de/ , accessed on 20 February 2025), allowing comparison between strain A-9 T and reference type strains from the DSMZ database [ ]. ..

    Article Title: Genomic and Pangenomic Insights into Aeromonas salmonicida subsp. oncorhynchi subsp. nov.
    Article Snippet: .. The digital DNA–DNA hybridization (dDDH) analysis was performed using the Type Strain Genome Server (TYGS, https://tygs.dsmz.de/, accessed on 20 February 2025), allowing comparison between strain A-9T and reference type strains from the DSMZ database [16]. ..

    Generated:

    Article Title: Spread of the novel vancomycin-resistant Enterococcus faecium strain ST1299/vanA from local level in Germany to cross-border level in Austria, 2018 to 2022
    Article Snippet: .. The phylogram including the closest related isolates was generated using the Type Strain Genome Server (TYGS, https://tygs.dsmz.de) and the dDDH method [35], and edited with InkSkape version 1.3.2 (https:// inkscape.org). ..



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    DSMZ type strain genome server
    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server <t>(TYGS),</t> places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
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    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server <t>(TYGS),</t> places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
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    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server <t>(TYGS),</t> places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
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    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server <t>(TYGS),</t> places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
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    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server <t>(TYGS),</t> places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.
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    Image Search Results


    (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server (TYGS), places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.

    Journal: bioRxiv

    Article Title: Exposure to third generation cephalosporin induces L-form transition in Shigella sonnei , potentially acting as a bacterial reservoir for persistent infection

    doi: 10.1101/2025.07.17.665312

    Figure Lengend Snippet: (A) Circular map of the 4.57 Mb chromosome of S. sonnei HK8. The concentric rings, from the outside in, represent: (1-2) COG functional categories and coding sequences (CDS) on the positive strand; (3) RNA genes; (4-5) CDS and COG categories on the negative strand; (6) GC content relative to the mean; and (7) GC skew [(G-C)/(G+C)]. (B) Whole-genome phylogenomic tree illustrating the evolutionary position of S. sonnei HK8. The analysis, performed using the Type Strain Genome Server (TYGS), places HK8 (highlighted in red) directly adjacent to the Shigella sonnei ATCC 29930 type strain, confirming its species identity. The tree scale indicates the evolutionary distance. (C) Bar chart showing the absolute counts of putative virulence-associated genes in the HK8 genome, categorized by confidence level. The analysis identified a large number of genes with homology to “Potential Non-secreted Virulence factors” and a substantial fraction classified as “Unknown.” Genes with stronger evidence were categorized as “Non-secreted Virulence factors,” “Secreted Virulence factors,” and “Potential Secreted Virulence factors,” providing a quantitative overview of the isolate’s pathogenic potential.

    Article Snippet: For comprehensive genome-based phylogenomic analysis and strain-level classification, the assembled genome was submitted to the Type Strain Genome Server (TYGS) ( https://tygs.dsmz.de/ ).

    Techniques: Functional Assay